Developmental Programming in Response to Maternal Overnutrition

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Developmental Programming in Response to Maternal Overnutrition

Metabolic disorders have seen an increased prevalence in recent years in developed as well as developing countries. While it is clear lifestyle choices and habits have contributed to this epidemic, mounting evidence suggests the nutritional milieu during critical stages of development in early life can "program" individuals to develop the metabolic syndrome later in life. Extensive epidemiologi...

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Dietary Proteins, Developmental Programming, and Potential Implication in Maternal Obesity

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The prevalence of obesity, especially in women of child-bearing age, is a global health concern. In addition to increasing the immediate risk of gestational complications, there is accumulating evidence that maternal obesity also has long-term consequences for the offspring. The concept of developmental programming describes the process in which an environmental stimulus, including altered nutr...

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The incidence of obesity and metabolic diseases is dramatically high in rapidly developing countries. Causes have been related to intrinsic ethnic features with development of a thrifty genotype for adapting to food scarcity, prenatal programming by undernutrition, and postnatal exposure to obesogenic lifestyle. Observational studies in humans and experimental studies in animal models evidence ...

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[Impact of maternal overnutrition on the periconceptional period].

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ژورنال

عنوان ژورنال: Frontiers in Genetics

سال: 2011

ISSN: 1664-8021

DOI: 10.3389/fgene.2011.00027